HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 10728935, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1H-Pyrrole-2-carboxylic acid, 5-methyl-, ethyl ester | HCID 96598 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 10728935 | HCID 10728935 | — |
Reaction Steps
Ethyl 5-methyl-1H-pyrrole-2-carboxylate (1.1 g) and benzyl bromide (1.35 g) in N,N-dimethylformamide (30 mL) was treated with NaH (95%, 0.5 g) overnight. The reaction was quenched with ice water. The mixture was diluted with ethyl acetate and washed with brine. The organic layer was dried over Na2SO4, filtered, and concentrated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266877B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-fb65a11dcb41491890458808cfd0aa40 |
| Source note | uspto-grants-2016_02 |