Aluminium lithium hydride → HCID 89498332, compound

Participants

Reaction Steps

To a cooled (0° C.) solution of EXAMPLE 145D (3.7 g) in tetrahydrofuran (20 mL) was added lithium aluminum hydride (720 mg). The cooling bath was removed, and the reaction mixture was stirred at room temperature for 3 hours. The reaction was quenched by the sequential addition of water (0.8 mL) and 15% aqueous NaOH solution (2 mL). The mixture was dried with MgSO4, filtered and concentrated to give the title compound, which was used in the subsequent step without further purification.

Provenance & Evidence