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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1779254Generated: November 1, 2026

HCID 90060273, compound → HCID 90060368, compound

https://huagongshe.com/reaction/1779254

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 90060273HCID 90060273—
SolventHydrogen chloride-ethyl acetateHCID 21866389—
ProductHCID 90060368HCID 90060368112.2%

Reaction Steps

tert-Butyl [(S)-2-(4-but-2-ynyloxy-phenyl)-1-dimethylcarbamoyl-ethyl]-carbamate (227 mg, 0.630 mmol) was dissolved in a solution (10 mL) of 1 M hydrogen chloride/ethyl acetate, and the mixture was stirred at room temperature for 7 hours. The reaction mixture was concentrated under reduced pressure to obtain the title compound (184 mg, 94%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266853B2
Source datasetuspto-grants-2016_02
ORD IDord-1a86a9e484904ddda779a21322f88786
Source noteuspto-grants-2016_02