HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 90060273, compound → HCID 90060368, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 90060273 | HCID 90060273 | — |
| Solvent | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Product | HCID 90060368 | HCID 90060368 | 112.2% |
Reaction Steps
tert-Butyl [(S)-2-(4-but-2-ynyloxy-phenyl)-1-dimethylcarbamoyl-ethyl]-carbamate (227 mg, 0.630 mmol) was dissolved in a solution (10 mL) of 1 M hydrogen chloride/ethyl acetate, and the mixture was stirred at room temperature for 7 hours. The reaction mixture was concentrated under reduced pressure to obtain the title compound (184 mg, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266853B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-1a86a9e484904ddda779a21322f88786 |
| Source note | uspto-grants-2016_02 |