(2-Octylbenzo[1,3]dioxol-5-yl)methanol → 5-Octyloxy-2-[4-(2-octylbenzo[1,3]dioxol-5-ylmethoxy)-phenyl]pyrimidine

HRID 1779264Notes

Reaction equation

HRID 1779264 reaction equation
[CH2:1]([O:9][C:10]1[CH:11]=[N:12][C:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)=[N:14][CH:15]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH2:23]([CH:31]1[O:35][C:34]2[CH:36]=[CH:37][C:38]([CH2:40]O)=[CH:39][C:33]=2[O:32]1)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>>[CH2:1]([O:9][C:10]1[CH:15]=[N:14][C:13]([C:16]2[CH:17]=[CH:18][C:19]([O:22][CH2:40][C:38]3[CH:37]=[CH:36][C:34]4[O:35][CH:31]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[O:32][C:33]=4[CH:39]=3)=[CH:20][CH:21]=2)=[N:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

3

Reactant 2

HCID 19050319(2-Octylbenzo[1,3]dioxol-5-yl)methanolHCID 135708811Phenol, 4-[5-(octyloxy)-2-pyrimidinyl]-

Product 1

HCID 190504325-Octyloxy-2-[4-(2-octylbenzo[1,3]dioxol-5-ylmethoxy)-phenyl]pyrimidine

Procedure

By Mitsunobu etherification of 4-(5-octyloxypyrimidin-2-yl)phenol using (2-octylbenzo[1,3]dioxol-5-yl)methanol.

Sources & evidence

ORD record
ord-64d608dfa237445592a3774209a7a555
Source dataset
uspto-grants-1997_05
Patent number
US05626791

Reaction notes

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