Sodium Acetate → HCID 86750787, compound

HRID 1779336Notes

Reaction equation

HRID 1779336 reaction equation
C[CH2:2][C:3](=O)[C:4]([O-:6])=[O:5].Cl.[N+:9]([C:12]1[CH:13]=[C:14]([NH:18][NH2:19])[CH:15]=[CH:16][CH:17]=1)([O-:11])=[O:10].[C:20]([O-])(=O)C.[Na+]>O.C(O)C.O.C(O)C>[N+:9]([C:12]1[CH:13]=[C:14]([NH:18][N:19]=[C:3]([CH3:2])[C:4]([O:6][CH3:20])=[O:5])[CH:15]=[CH:16][CH:17]=1)([O-:11])=[O:10]

Participants

7

Reactant 3

HCID 517045Sodium AcetateHCID 35932772-KetobutyrateHCID 54642853-Nitrophenylhydrazinium(1+) chloride

Product 1

HCID 86750787HCID 86750787, compoundYield 89.2%

Reagents, catalysts & solvents 3

HCID 702EthanolSolventHCID 962WaterSolventHCID 19096565Water ethanolSolvent

Procedure

A solution of methylpyruvate (31.8 g, 0.312 mol) in water-ethanol (10:1, 100 ml) was slowly added to a hot solution of 3-nitrophenylhydrazine hydrochloride (59.2 g, 0.312 mol) and sodium acetate (28.0 g, 0.34 mol) in water and ethanol (5:7, 1200 ml). The mixture was stirred at room temperature for 2 h during which time a heavy yellow precipitate developed. The precipitate was filtered, washed with cold water (2000 ml), and dried to give the product (66 g) as a yellow solid.

Workup

  1. filtrationThe precipitate was filtered
  2. washwashed with cold water (2000 ml)
  3. customdried

Sources & evidence

ORD record
ord-b5f6772d6bb44f9c92ee892b0518bfbe
Source dataset
uspto-grants-1997_05
Patent number
US05627177

Reaction notes

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