Hexane → HCID 67648377, compound

Participants

Reaction Steps

0.4 g (10 mmol) of sodium hydride dispersion (approx. 60%) is added, with stirring, to a solution of 1.5 g (2.5 mmol) of (E)-1,5,10,14-tetra-BOC-1,5,10,14-tetraazatetradec-7-ene in 21.5 ml of DMF. The mixture is stirred for 15 min. at room temperature; then 1.06 ml (10 mmol) of bromomethyl-cyclopropane (approx. 90% ) are added to the reaction mixture and stirring is continued for 90 h at room temperature. Working up analogously to Example 1a) yields the title compound in the form of a colourless resin, Rf value=0.47 (silica gel/ethyl acetate:hexane (2:3)).

Provenance & Evidence