Hydrochloric Acid → HCID 19956430, compound

Participants

Reaction Steps

A mixture of 0.265 g (0.859 mmol) of (E)-1,4-bis(3-propylhexahydro-pyrimidin-1-yl)but-2-ene, 3 ml of methanol and 3.4 ml (6.8 mmol) of 2N hydrochloric acid is heated for 19 h under reflux and is then concentrated by evaporation in vacuo. Recrystallisation of the residue from methanol/water yields the title compound, m.p. >260° C. 1H-NMR (D2O): δ0.96(t,6H); 1.62-1.76(m,4H); 2.05-2.16(m,4H); 3.02(t,4H); 3.11-3.18(m,8H); 3.77(d,4H); 6.03-6.06(m,2H).

Provenance & Evidence