HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic Acid → HCID 131719716, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic Acid | HCID 971 | — |
| Reactant | 4-(3-chloropropoxy)-1H-indole | HCID 11694169 | — |
| Reactant | HCID 21268253 | HCID 21268253 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 131719716 | HCID 131719716 | — |
Reaction Steps
The title compound was prepared in similar fashion from 1-chloro-3-(1H-indole-4-oxy)propane and 1,5-dihydrospiro[4H-2-benzopyran-4,4'-piperidine]. The resulting free base was dissolved in ethyl acetate, and precipitated with one equivalent of oxalic acid in ethyl acetate in 69% overall yield as a foam. FDMS m/e=376 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05627196 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-ead95ad574264ebf9485172ad6f27770 |
| Source note | uspto-grants-1997_05 |