HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Nitro-1H-indole → 6-Nitro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Nitro-1H-indole | HCID 78502 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 6-Nitro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole | HCID 21268269 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Preparation 30 from 6-nitroindole (6.0 g, 37 mmol) and 4-piperidone hydrochloride hydrate (11.4 g, 74 mmol). The product was isolated as an orange solid. Yield 8.8 g (97%). mp 247°-250° C. (dec.) FDMS m/e=243 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05627196 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-248359412fb94c5f82038a43e45741c5 |
| Source note | uspto-grants-1997_05 |