HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloroindole → 6-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloroindole | HCID 87111 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 6-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 10059854 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Preparation 30 from 6-chloroindole (4.0 g, 26 mmol) and 4-piperidone hydrochloride hydrate (8.0 g, 52 mmol). The product was isolated as a yellow solid. Yield 3.7 g (61%). mp 181°-185° C. FDMS m/e=234 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05627196 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-fe9b0890a7184f3198a76fd2ac93331c |
| Source note | uspto-grants-1997_05 |