Acetic Anhydride → HCID 11041076, compound

Participants

Reaction Steps

The thus-obtained 3,7-dimethyl-4-oxo-7-octenoic acid is then dissolved in a solvent and an equivalent amount or a somewhat excessive amount of acetic anhydride is added thereto and heated under reflux in the presence of an acid catalyst, whereby the acid is cyclized and dehydrated along with isomerization of the terminal double bond to give 3,7-dimethyl-2,6-octadien-4-olide. As the solvent in this process, usable is a hydrocarbon solvent such as pentane, hexane, heptane, benzene, toluene, xylene or the like. Especially preferred is toluene. As the acid catalyst, usable is an organic acid such as acetic acid, para-toluene-sulfonic acid, camphor-sulfonic acid or the like.

Provenance & Evidence