HCID 19956651, compound → HCID 88248083, compound

HRID 1779738Notes

Reaction equation

HRID 1779738 reaction equation
[C:1]([O:4][CH2:5][C@@H:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:7][OH:8])(=S)[NH2:2].[C:15]([O:18]CC(C1C=CC=CC=1)CO)(=[S:17])[NH2:16]>>[C:1](=[O:4])([OH:18])[NH2:2].[C:15]([CH:5]([OH:4])[C@@H:6]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)[CH2:7][OH:8])(=[S:17])[NH2:16]

Participants

3

Reactant 2

HCID 19956651HCID 19956651, compoundHCID 88249134HCID 88249134, compound

Product 1

HCID 88248083HCID 88248083, compound

Procedure

Example V was repeated using as the starting material (S)-2-phenyl-1,3-propandiol monothiocarbamate prepared in Example IV, instead of 2-phenyl-1,3-propandiol monothiocarbamate racemate. The title compound thus obtained was tested for optical purity with a high pressure liquid chromatograph equipped with a column for separating optical isomers.

Sources & evidence

ORD record
ord-a7793c7875854c85b5c7d99e1242d9f7
Source dataset
uspto-grants-1997_05
Patent number
US05627300

Reaction notes

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