Sodium Hydroxide → HCID 53655626, compound

HRID 1779923Notes

Reaction equation

HRID 1779923 reaction equation
[Br:1][CH:2]1[CH2:38][C@@H:37]([CH3:39])[CH2:36][O:35][C@@:3]21[C@@H:7]([CH3:8])[C@@H:6]1[C@:9]3([CH3:34])[C@@H:22]([CH2:23][C@@H:5]1[O:4]2)[C@H:21]1[C@@H:12]([C@:13]2([CH3:25])[C@@H:18]([CH2:19][CH2:20]1)[CH2:17][C@@H:16]([OH:24])[CH2:15][CH2:14]2)[C@@H:11]([OH:26])[C@@H:10]3[O:27]C(=O)C(Cl)(Cl)Cl.[OH-].[Na+]>O.C(O)C>[Br:1][CH:2]1[CH2:38][C@@H:37]([CH3:39])[CH2:36][O:35][C@@:3]21[C@@H:7]([CH3:8])[C@@H:6]1[C@:9]3([CH3:34])[C@@H:22]([CH2:23][C@@H:5]1[O:4]2)[C@H:21]1[C@@H:12]([C@:13]2([CH3:25])[C@@H:18]([CH2:19][CH2:20]1)[CH2:17][C@@H:16]([OH:24])[CH2:15][CH2:14]2)[C@@H:11]([OH:26])[C@@H:10]3[OH:27]

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 54097936HCID 54097936, compound

Product 1

HCID 53655626HCID 53655626, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

Using the procedure described in J. Chem. Soc., 1956, 4330, (3β,5α,11β,12α,25R)-23-bromo-12-(trichloroacetoxy)spirostan-3,11-diol was saponified with sodium hydroxide in water and ethanol to give the title compound.

Sources & evidence

ORD record
ord-e406f71b428e4a019c2e7353937d2885
Source dataset
uspto-grants-1997_05
Patent number
US05629295

Reaction notes

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