HCID 54097936, compound → HCID 54358548, compound

HRID 1779924Notes

Reaction equation

HRID 1779924 reaction equation
Br[CH:2]1[CH2:38][C@@H:37]([CH3:39])[CH2:36][O:35][C@@:3]21[C@@H:7]([CH3:8])[C@@H:6]1[C@:9]3([CH3:34])[C@@H:22]([CH2:23][C@@H:5]1[O:4]2)[C@H:21]1[C@@H:12]([C@:13]2([CH3:25])[C@@H:18]([CH2:19][CH2:20]1)[CH2:17][C@@H:16]([OH:24])[CH2:15][CH2:14]2)[C@@H:11]([OH:26])[C@@H:10]3[O:27]C(=O)C(Cl)(Cl)Cl>[Zn].C(O)(=O)C>[CH3:8][C@@H:7]1[C@:3]2([O:35][CH2:36][C@H:37]([CH3:39])[CH2:38][CH2:2]2)[O:4][C@H:5]2[CH2:23][C@@H:22]3[C@@:9]([CH3:34])([C@@H:6]12)[C@@H:10]([OH:27])[C@H:11]([OH:26])[C@H:12]1[C@H:21]3[CH2:20][CH2:19][C@@H:18]2[C@:13]1([CH3:25])[CH2:14][CH2:15][C@H:16]([OH:24])[CH2:17]2

Participants

4

Reactant 1

HCID 54097936HCID 54097936, compound

Product 1

HCID 54358548HCID 54358548, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 176Acetic AcidSolvent

Procedure

Using the procedure described in J. Chem. Soc., 1956, 4330, (3β,5α,11β,12α,25R)-23-bromo-12-(trichloroacetoxy)-spirostan-3,11-diol was reduced with zinc and acetic acid to give the title compound.

Sources & evidence

ORD record
ord-d907688a615d49d59fedf846d7d72654
Source dataset
uspto-grants-1997_05
Patent number
US05629295

Reaction notes

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