HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+)-Hecogenin → Spirostan-3,12-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+)-Hecogenin | HCID 91453 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Spirostan-3,12-diol | HCID 167555 | — |
Reaction Steps
Using the procedure described in J. Am. Chem. Soc., 1954, 76, 4013, (3β,5α,25R)-spirostan-3-ol-12-one was reduced with lithium aluminum hydride in ether to give a mixture of C-12 alcohols from which the title compound was isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05629295 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-b66b47d7a90c4f9a92b14dd1b0ce9416 |
| Source note | uspto-grants-1997_05 |