Methyl iodide → HCID 53816588, compound

HRID 1779982Notes

Reaction equation

HRID 1779982 reaction equation
[CH3:1]I.[NH2:3][C:4]1[N:8]([C:9]2[C:14]([Cl:15])=[CH:13][C:12]([C:16]([F:19])([F:18])[F:17])=[CH:11][C:10]=2[Br:20])[N:7]=[C:6]([C:21](=[S:23])[NH2:22])[C:5]=1[S:24]([CH3:26])=[O:25]>>[CH3:1][S:23][C:21]([C:6]1[C:5]([S:24]([CH3:26])=[O:25])=[C:4]([NH2:3])[N:8]([C:9]2[C:14]([Cl:15])=[CH:13][C:12]([C:16]([F:17])([F:18])[F:19])=[CH:11][C:10]=2[Br:20])[N:7]=1)=[NH:22]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 10298328HCID 10298328, compound

Product 1

HCID 53816588HCID 53816588, compound

Procedure

In a manner similar to that described in EXAMPLE 2, methyl iodide was reacted with 5-amino-1-[2-bromo-6-chloro-4-(trifluoromethyl)phenyl]-4-methylsulfinyl-1H-pyrazole-3-carbothioamide (Compound 6, prepared as described in applicants' concurrently filed, copending application referenced in EXAMPLE 2 above) to give 5-amino-1-[2-bromo-6-chloro-4-(trifluoromethyl)phenyl]-4-methylsulfinyl-1H-pyrazole-3-carboximidothioic acid methyl ester having a melting point of 203.5° C. compound is referred to hereinafter as Compound 4.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-803d5ffccf4c493eb1362bfa1184ce6a
Source dataset
uspto-grants-1997_05
Patent number
US05629335

Reaction notes

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