Propargyl bromide → HCID 19049272, compound

HRID 1780020Notes

Reaction equation

HRID 1780020 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:10]2[O:20][C:19]3[CH:18]=[C:17]([OH:21])[CH:16]=[C:15]([OH:22])[C:14]=3[C:12](=[O:13])[CH:11]=2)=[CH:7][C:8]=1[OH:9].[CH2:23](Br)[C:24]#[CH:25]>>[CH2:23]([O:22][C:15]1[C:14]2[C:12](=[O:13])[CH:11]=[C:10]([C:6]3[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[C:8]([O:9][CH2:4][C:3]#[CH:8])[CH:7]=3)[O:20][C:19]=2[CH:18]=[C:17]([O:21][CH2:7][C:6]#[CH:5])[CH:16]=1)[C:24]#[CH:25]

Participants

3

Reactant 2

HCID 7842Propargyl bromideHCID 5281612Diosmetin

Product 1

HCID 19049272HCID 19049272, compound

Procedure

30 g of diosmetin are alkylated with propargyl bromide under the conditions of Example 3 to yield, after recrystallisation from isopropanol, 32 g of the title compound in pure form, m.p.: 196° C.

Workup

  1. customto yield
  2. customafter recrystallisation from isopropanol, 32 g of the title compound in pure form, m.p.: 196° C.

Sources & evidence

ORD record
ord-4619fb58e87443f98bf0bbcd6d346547
Source dataset
uspto-grants-1997_05
Patent number
US05629339

Reaction notes

Loading…