HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylamine → 1-Butanone, 2-(dimethylamino)-1-(4-(dimethylamino)phenyl)-2-(phenylmethyl)-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylamine | HCID 674 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2-Benzyl-2-(dimethylamino)-1-(4-fluorophenyl)butan-1-one | HCID 19360599 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 1-Butanone, 2-(dimethylamino)-1-(4-(dimethylamino)phenyl)-2-(phenylmethyl)- | HCID 164106 | — |
Reaktionsschritte
A stirred autoclave is filled with 50 g (0.167 mol) of 1-(4-fluorophenyl)-2-dimethylamino-2-benzylbutan-1-one (crude product from B), 300 ml of dimethylformamide and 23.1 g (0.167 mol) of potassium carbonate. 22.6 g (0.5 mol) of dimethylamine are then added under pressure (3-4 bar). The mixture is heated to 100° and stirred at this temperature for 24 hours.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05629356 |
| Quelldatensatz | uspto-grants-1997_05 |
| ORD ID | ord-ac1fbe2e2f934b1b9135acf2a1e792ac |
| Quellennotiz | uspto-grants-1997_05 |