2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine → N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-4-ethoxy-2-methoxybenzamide

HRID 178016Notes

Reaction equation

HRID 178016 reaction equation
[Cl:13][c:14]1[c:15]([O:25][CH2:26][CH3:27])[cH:16][c:17]([O:23][CH3:24])[c:18]([C:19](=[O:20])[OH:21])[cH:22]1.[NH2:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[CH2:7][N:6]([CH3:12])[CH2:5][CH2:4]2>>[NH:1]([c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[CH2:7][N:6]([CH3:12])[CH2:5][CH2:4]2)[C:19]([c:18]1[c:17]([O:23][CH3:24])[cH:16][c:15]([O:25][CH2:26][CH3:27])[c:14]([Cl:13])[cH:22]1)=[O:20]

Participants

3

Reactant 2

HCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 217104695-Chloro-4-ethoxy-2-methoxybenzoic acid

Product 1

HCID 18687426N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-4-ethoxy-2-methoxybenzamide

Sources & evidence

ORD record
ord-190843059af24d37a3b51bc719c2bc9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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