反应详情

The product of Example 3 (14.5 g, 90 mM) in 48% of HBr/acetic acid (100 ml) was left at room temperature overnight. The reaction was poured onto water (500 ml) and extracted with IPE 2x). The organic phase was washed with water, dried and evaporated to give the crystalline product (22 g) m.p. (cyclohexane).

1. additionThe reaction was poured onto water (500 ml)
2. extractionextracted with IPE 2x)
3. washThe organic phase was washed with water
4. customdried
5. customevaporated