4-Nitrophenyl chloroformate → HCID 70059124, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 30, but using 500 mg (0.76 mmol) of 1-{(2S,3S)-3-[N2 -(p-methylaminophenoxy)acetyl-L-asparaginyl]amino-2-hydroxy-4-phenylbutyryl}-N-t-butyl-L-prolinamide hydrochloride (prepared as described in Example 20) and 236 mg (1.13 mmol) of 4-nitrophenoxycarbonyl chloride, 121 mg of the title compound were obtained as a colorless powder, melting at 116°-119° C.

Provenance & Evidence