Benzyl chloroformate → HCID 70048501, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 30, but using 40 mg (61.2 μmol) of 1-{(2S,3S)-3-[N2 -(4-aminocyclohexyloxy)acetyl-L-asparaginyl]amino-2-hydroxy-4-phenylbutyryl}-N-t-butyl-L-prolinamide hydrochloride (prepared as described in Example 58) and 0.01 ml (67.3 μmol) of benzyloxycarbonyl chloride, 22 mg of the title compound were obtained as a colorless powder, melting at 109°-114° C.

Provenance & Evidence