HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57010663, compound → HCID 70058296, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57010663 | HCID 57010663 | — |
| Reactant | (2S,3S)-3-(N2-benzyloxycarbonyl-L-asparaginyl)amino-2-hydroxy-4-phenylbutyric acid | HCID 57125825 | — |
| Product | HCID 70058296 | HCID 70058296 | 65.3% |
Reaction Steps
79 mg (0.24 mmol) of N-benzyloxycarbonyl-N-(1,1-dimethyl-2-hydroxypropyl)-L-prolinamide were subjected to debenzyloxycarbonylation in a similar manner to that described in Example 17, and then the resulting product was condensed with 106 mg (0.24 mmol) of (2S,3S)-3-(N2 -benzyloxycarbonyl-L-asparaginyl)amino-2-hydroxy-4-phenylbutyric acid in a similar manner to that described in Example 1, to give 98 mg of the title compound as a colorless powder, melting at 102°-104° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05629406 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-fb2a2a17208942e7a8240f8afc3caa61 |
| Source note | uspto-grants-1997_05 |