HCID 131715074, compound → HCID 9851505, compound

HRID 1780535Notes

Reaction equation

HRID 1780535 reaction equation
[CH3:1][CH:2]([N:11]([CH3:13])[CH3:12])[C@H:3]([OH:10])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1.Cl>ClCCl>[CH3:1][CH:2]([N:11]([CH3:12])[CH3:13])[C@H:3]([OH:10])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 1

HCID 131715074HCID 131715074, compound

Product 1

HCID 9851505HCID 9851505, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In 2.5 ml of a 20% aqueous gelatin solution (liquified by warming) is dissolved 1 g of methylephedrine hydrochloride and the solution is added to 10 ml of a 20% dichloromethane solution of polylactic acid (average mol. wt. 50000). The mixture is worked up in the same manner as Example 1 to give methylephedrine microcapsules for injection.

Sources & evidence

ORD record
ord-a11007f9250a442e8697a75496b703fb
Source dataset
uspto-grants-1997_05
Patent number
US05631020

Reaction notes

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