Water → HCID 19048026, compound

Participants

Reaction Steps

Phenothiazine, 0.5 g/0.0025M, and p-anisidine, 0.307 g/0.0025M, were dissolved in 50 ml of methanol and stirred at ambient temperature. Periodic acid, 3.4 g/0.015M, was dissolved in 40 ml of methanol and the solution added in one portion to the stirring phenothiazine mixture. The reaction mixture was stirred for 20 minutes and then poured into 100 ml of water with solid residue being collected by a Buchner funnel. The solid was stirred with 200 ml of a 1:1 mixture of MeOH/H2O and collected. The red-brown solid was dried to yield 0.72 g (91% theory) of the desired product having a melting point of 135°-136° C. (lit. 148°-149° C.).

Provenance & Evidence