Borane → (4-Phenoxyphenyl)methanol

Participants

Reaction Steps

A 0° C. solution of 4-phenoxybenzaldehyde (5.0 g, 25.2 mmol) in 10 mL THF under an atmosphere of dry N2 was treated with borane (1.0M in THF, 11.25 mL) for 1 hour. A saturated NH4Cl solution was added, and the mixture was diluted with ethyl acetate. The organic layer was washed with 1M HCl, 5% NaHCO3 and brine, dried and concentrated in vacuo to give the title compound in 92% yield.

Provenance & Evidence