5-Phenyl-1-pentanol → Benzenepentanal

Participants

Reaction Steps

To a solution of 5-phenylpentanol (15.0 g, 91 mmol) in methylene chloride was added pyridinium chlorochromate (24.6 g, 114 mmol) under an atmosphere of dry nitrogen at room temperature. After 18 hours, the mixture was filtered through a bed of Celite®, and purified by flash chromatography on silica gel eluting with 10% ethyl acetate in hexane to give the aldehyde in 57% yield.

Provenance & Evidence