Sodium Hydroxide → HCID 14623875, compound

HRID 1781254Notes

Reaction equation

HRID 1781254 reaction equation
[O:1]=[C:2]1[CH2:5][C:4]([C:11]([O:13]CC)=[O:12])([C:6]([O:8]CC)=[O:7])[NH:3]1.[OH-].[Na+:17]>CO>[O:1]=[C:2]1[CH2:5][C:4]([C:6]([O-:8])=[O:7])([C:11]([O-:13])=[O:12])[NH:3]1.[Na+:17].[Na+:17]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19045180HCID 19045180, compound

Product 1

HCID 14623875HCID 14623875, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1(c) 5.72 g of diethyl 2-oxoazetidine-4,4-dicarboxylate (prepared as described above) were dissolved in 25 ml of methanol. 53.2 ml of a 1N aqueous solution of sodium hydroxide were added to the resulting solution, and the mixture was stirred at room temperature for 1 day. At the end of this time, the reaction mixture was concentrated by evaporation under reduced pressure to give crystals, which were washed with methanol and with diethyl ether to give 5.3 g of the title compound as crystals.

Workup

  1. concentrationAt the end of this time, the reaction mixture was concentrated by evaporation under reduced pressure
  2. customto give crystals, which
  3. washwere washed with methanol and with diethyl ether

Sources & evidence

ORD record
ord-70e6a23c877648c4afd2e249917b361d
Source dataset
uspto-grants-1997_05
Patent number
US05633243

Reaction notes

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