反应详情

2(c) 8.74 ml of a 1N aqueous solution of sodium hydroxide were added to a solution of 1.0 g of diethyl 2-oxopyrrolidine-5,5-dicarboxylate (prepared as described above) in 10 ml of ethanol, and the mixture was stirred at room temperature for 3 days. At the end of this time, the solvent was removed by distillation under reduced pressure, and the residual crystals were washed with acetone and dried to give 950 mg of sodium 2-oxopyrrolidine-5,5-dicarboxylate as a colorless powder.

1. customAt the end of this time, the solvent was removed by distillation under reduced pressure
2. washthe residual crystals were washed with acetone
3. customdried