Methanesulfonate → HCID 54191993, compound

Participants

Reaction Steps

Compound 24 (570 mg, 0.66 mmol) was converted into its methane sulfonyl derivative exactly as described for the preparation of 10 to give 25 (530 mg, 85.3%) as a syrup after chromatography on silica gel using (hexane:ethyl acetate; 3:2) as eluant; [α]D +76.6° (c 0.57, chloroform). 1H-n.m.r. (CDCl3): δ5.19(t, 1H, J2,3 =J3,4 10.0 Hz, H-3), 4.90(d, 1H, J1',2' 3.8 Hz, H-1'), 4.82(d, 1H, J1,2 3.8 Hz, H-1), 3.57(s, 3H, OCH3), 3.00(s, 3H, CH3SO2), 2.23 and 2.03(s, 3H each, 2×Ac).

Provenance & Evidence