HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 1,3-Dihydro-1-(2-bromoethyl)-3-isopropenyl-2h-benzimidazol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1,3-Dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-one | HCID 100278 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1,3-Dihydro-1-(2-bromoethyl)-3-isopropenyl-2h-benzimidazol-2-one | HCID 19045390 | — |
Reaction Steps
1-Isopropenylbenzimidazolone (J. Davol, J. Chem. Soc., 1960, 308) was alkylated with 1,2-dibromoethane using sodium hydride in DMF. The product was purified by chromatography and crystallization from cyclohexane to give 1-isopropenyl-3-(2-bromoethyl)benzimidazolone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05633247 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-e8fb55e1737e4827b7e769d1e042ed5c |
| Source note | uspto-grants-1997_05 |