N-Benzoyl-4-piperidone → HCID 19045373, compound

HRID 1781433Notes

Reaction equation

HRID 1781433 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[C:12](=[O:14])[CH3:13].[C:15]([N:23]1[CH2:28][CH2:27][C:26](=O)[CH2:25][CH2:24]1)(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:15]([N:23]1[CH2:28][CH2:27][C:26]2([CH2:13][C:12](=[O:14])[C:3]3[CH:4]=[C:5]([S:8]([CH3:11])(=[O:10])=[O:9])[CH:6]=[CH:7][C:2]=3[O:1]2)[CH2:25][CH2:24]1)(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 90583N-Benzoyl-4-piperidoneHCID 12791432HCID 12791432, compound

Product 1

HCID 19045373HCID 19045373, compound

Procedure

2'-Hydroxy-5'-methanesulfonylacetophenone and 1-benzoyl-4-piperidone were condensed according to the method of Example 434 to give the ketone as a white solid, m.p. 155°-157° C.

Workup

  1. customcondensed

Sources & evidence

ORD record
ord-36f4e07ece4345459e811bf56f018f8b
Source dataset
uspto-grants-1997_05
Patent number
US05633247

Reaction notes

Loading…