N-Acetyl-4-piperidone → HCID 19045553, compound

HRID 1781434Notes

Reaction equation

HRID 1781434 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[C:12](=[O:14])[CH3:13].[C:15]([N:18]1[CH2:23][CH2:22][C:21](=O)[CH2:20][CH2:19]1)(=[O:17])[CH3:16]>>[C:15]([N:18]1[CH2:23][CH2:22][C:21]2([CH2:13][C:12](=[O:14])[C:3]3[CH:4]=[C:5]([S:8]([CH3:11])(=[O:10])=[O:9])[CH:6]=[CH:7][C:2]=3[O:1]2)[CH2:20][CH2:19]1)(=[O:17])[CH3:16]

Participants

3

Reactant 2

HCID 122563N-Acetyl-4-piperidoneHCID 12791432HCID 12791432, compound

Product 1

HCID 19045553HCID 19045553, compound

Procedure

2'-Hydroxy-5'-methanesulfonylacetophenone and 1-acetyl-4-piperidone were condensed according to the method of Example 434 to give the ketone as a white solid, m.p. 105°-110° C.

Workup

  1. customcondensed

Sources & evidence

ORD record
ord-67abe4c548034256ae6714c550d7c0b3
Source dataset
uspto-grants-1997_05
Patent number
US05633247

Reaction notes

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