1-Adamantaneacetyl chloride → Sulfamic acid[adamantaneacetyl]-2,6-bis[1-methylethyl]phenyl ester

HRID 1781454Notes

Reaction equation

HRID 1781454 reaction equation
CC(C1C=CC=C(C(C)C)C=1CC([C:16]1[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:29])(=[O:28])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)=O)C.C(C1C=CC=C(C(C)C)C=1CC(Cl)=O)(C)C.[C:49]12([CH2:59][C:60](Cl)=[O:61])[CH2:58][CH:53]3[CH2:54][CH:55]([CH2:57][CH:51]([CH2:52]3)[CH2:50]1)[CH2:56]2>>[C:49]12([CH2:59][C:60]([C:16]3[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:28])(=[O:29])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=3)=[O:61])[CH2:58][CH:53]3[CH2:54][CH:55]([CH2:57][CH:51]([CH2:52]3)[CH2:50]1)[CH2:56]2

Participants

4

Reactant 3

HCID 27718821-Adamantaneacetyl chlorideHCID 10226443Sulfamic acid[[2,6-bis(1-methylethyl)phenyl]-acetyl]-2,6-bis(1-methylethyl)phenyl esterHCID 193627822,6-Diisopropylphenylacetyl chloride

Product 1

HCID 131719260Sulfamic acid[adamantaneacetyl]-2,6-bis[1-methylethyl]phenyl ester

Procedure

This compound was prepared in the same manner as for the title compound of Example 1, except that 2,6-diisopropylphenylacetyl chloride was replaced with adamantaneacetyl chloride; 1HNMR(CDCl3):1.21 (d, 12H), 1.6-2.0 (m, 15H), 2.15 (s, 2H), 3.4 (m, 2H), 7.15-7.25 (m, 3H) ppm.

Sources & evidence

ORD record
ord-e954e282dfa64573998a8376e668ca24
Source dataset
uspto-grants-1997_05
Patent number
US05633287

Reaction notes

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