(2,5-Dimethoxyphenyl)acetyl chloride → Sulfamic acid[2,5-dimethoxyphenyl(acetyl)]-2,6-bis(1-methylethyl)phenyl ester

HRID 1781466Notes

Reaction equation

HRID 1781466 reaction equation
CC(C1C=CC=C(C(C)C)C=1CC([C:16]1[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:29])(=[O:28])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)=O)C.C(C1C=CC=C(C(C)C)C=1CC(Cl)=O)(C)C.[CH3:49][O:50][C:51]1[CH:56]=[CH:55][C:54]([O:57][CH3:58])=[CH:53][C:52]=1[CH2:59][C:60](Cl)=[O:61]>>[CH3:49][O:50][C:51]1[CH:56]=[CH:55][C:54]([O:57][CH3:58])=[CH:53][C:52]=1[CH2:59][C:60]([C:16]1[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:28])(=[O:29])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)=[O:61]

Participants

4

Reactant 3

HCID 596088(2,5-Dimethoxyphenyl)acetyl chlorideHCID 10226443Sulfamic acid[[2,6-bis(1-methylethyl)phenyl]-acetyl]-2,6-bis(1-methylethyl)phenyl esterHCID 193627822,6-Diisopropylphenylacetyl chloride

Product 1

HCID 19046540Sulfamic acid[2,5-dimethoxyphenyl(acetyl)]-2,6-bis(1-methylethyl)phenyl ester

Procedure

This compound was prepared in the same manner as for the title compound of Example 1, except that 2,6-diisopropylphenylacetyl chloride was replaced with 2,5-dimethoxyphenylacetyl chloride, mp 150°-152° C.

Sources & evidence

ORD record
ord-e2229a72666645d38244e073b8a88481
Source dataset
uspto-grants-1997_05
Patent number
US05633287

Reaction notes

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