2,4,6-Trimethoxyphenylacetic acid → Sulfamic acid[2,4,6-trimethoxyphenyl(acetyl)]-2,6-bis(1-methylethyl)phenyl ester

HRID 1781467Notes

Reaction equation

HRID 1781467 reaction equation
CC(C1C=CC=C(C(C)C)C=1CC([C:16]1[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:29])(=[O:28])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)=O)C.C(C1C=CC=C(C(C)C)C=1CC(O)=O)(C)C.[CH3:49][O:50][C:51]1[CH:56]=[C:55]([O:57][CH3:58])[CH:54]=[C:53]([O:59][CH3:60])[C:52]=1[CH2:61][C:62]([OH:64])=O>>[CH3:60][O:59][C:53]1[CH:54]=[C:55]([O:57][CH3:58])[CH:56]=[C:51]([O:50][CH3:49])[C:52]=1[CH2:61][C:62]([C:16]1[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:28])(=[O:29])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)=[O:64]

Participants

4

Reactant 3

HCID 52434732,4,6-Trimethoxyphenylacetic acidHCID 10226443Sulfamic acid[[2,6-bis(1-methylethyl)phenyl]-acetyl]-2,6-bis(1-methylethyl)phenyl esterHCID 152779902-(2,6-Diisopropylphenyl)acetic acid

Product 1

HCID 19046534Sulfamic acid[2,4,6-trimethoxyphenyl(acetyl)]-2,6-bis(1-methylethyl)phenyl ester

Procedure

This compound was prepared in the same manner as for the title compound of Example 1, except that 2,6-diisopropylphenylacetic acid was replaced with 2,4,6-trimethoxyphenylacetic acid, mp 159°-163° C.

Sources & evidence

ORD record
ord-19809ad545844ab1a8918acd129c31e2
Source dataset
uspto-grants-1997_05
Patent number
US05633287

Reaction notes

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