(2-(trifluoromethyl)phenyl)acetic acid → HCID 19046551, compound

HRID 1781473Notes

Reaction equation

HRID 1781473 reaction equation
CC(C1C=CC=C(C(C)C)C=1CC([C:16]1[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:29])(=[O:28])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)=O)C.C(C1C=CC=C(C(C)C)C=1CC(O)=O)(C)C.[F:49][C:50]([F:62])([F:61])[C:51]1[CH:56]=[CH:55][CH:54]=[CH:53][C:52]=1[CH2:57][C:58]([OH:60])=O>>[F:61][C:50]([F:49])([F:62])[C:51]1[CH:56]=[CH:55][CH:54]=[CH:53][C:52]=1[CH2:57][C:58]([C:16]1[C:17]([CH:30]([CH3:32])[CH3:31])=[C:18]([O:25][S:26](=[O:28])(=[O:29])[NH2:27])[C:19]([CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)=[O:60]

Participants

4

Reactant 3

HCID 594597(2-(trifluoromethyl)phenyl)acetic acidHCID 10226443Sulfamic acid[[2,6-bis(1-methylethyl)phenyl]-acetyl]-2,6-bis(1-methylethyl)phenyl esterHCID 152779902-(2,6-Diisopropylphenyl)acetic acid

Product 1

HCID 19046551HCID 19046551, compound

Procedure

This compound was prepared in the same manner as for the title compound of Example 1, except that 2,6-diisopropylphenylacetic acid was replaced with 2-trifluoromethylphenylacetic acid, mp 144°-149° C.

Sources & evidence

ORD record
ord-7dcd9edec46e48cb871afa158b778266
Source dataset
uspto-grants-1997_05
Patent number
US05633287

Reaction notes

Loading…