3-Pyridinemethanamine → HCID 178512112, compound

HRID 1781594Notes

Reaction equation

HRID 1781594 reaction equation
[N+:1]([NH:4][C:5]([NH2:7])=[NH:6])([O-:3])=[O:2].N[CH2:9][C:10]1[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=1>O>[N+:1]([NH:4][C:5]([NH:7][CH2:9][C:10]1[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=1)=[NH:6])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 310183-PyridinemethanamineHCID 86287517Nitroguanidine

Product 1

HCID 178512112HCID 178512112, compoundYield 48.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 0.53 g of nitroguanidine, 0.61 g of 3-(aminomethyl)pyridine and 10 ml of water was stirred for 1.5 hours at 70°-80° C. and allowed to stand over night at room temperature. The precipitate collected by filtration was washed with ethanol to obtain 0.48 g of N-nitro-N'-(3-pyridylmethyl)guanidine (Compound No. 12).

Workup

  1. waitto stand over night at room temperature
  2. filtrationThe precipitate collected by filtration
  3. washwas washed with ethanol

Sources & evidence

ORD record
ord-1bca00ba48324653a225f7149bb02d40
Source dataset
uspto-grants-1997_05
Patent number
US05633375

Reaction notes

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