HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1,2-Benzisothiazol-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Metaperiodic acid | HCID 65185 | — |
| Reactant | HCID 12242117 | HCID 12242117 | — |
| Product | 1,2-Benzisothiazol-3(2H)-one | HCID 17520 | — |
Reaction Steps
In this method, 2-(methylthio)benzamide is produced from 2-(methylthio)benzoyl chloride; oxidized with periodic acid to 2-(methylsulfinyl)benzamide; and cyclized in the presence of thionyl chloride to yield a 1,2-benzisothiazol-3-one. ##STR1## (B) Org. Prep. Proced. Int., 15, 315-319(1983)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05633384 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-66ff7f10eb6a48de846e496529f46089 |
| Source note | uspto-grants-1997_05 |