HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxy-3-methoxy-5-nitrobenzoic acid → 3,4-Dihydroxy-5-nitrobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxy-3-methoxy-5-nitrobenzoic acid | HCID 15527939 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | 3,4-Dihydroxy-5-nitrobenzoic acid | HCID 14450982 | — |
Reaction Steps
A solution of 2.6 g of 4-hydroxy-3-methoxy-5-nitrobenzoic acid in 26 ml of constant-boiling hydrobromic acid is heated under reflux for 2 hours. After cooling the solvent is distilled in a water-jet vacuum. The crystalline residue is recrystallized from 50 ml of water at boiling temperature. There is obtained 3,4-dihydroxy-5-nitrobenzoic acid in the form of yellow crystals of m.p. 224°-226°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05633371 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-f7329e3b88654b54961703a743b4acdf |
| Source note | uspto-grants-1997_05 |