HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo(d)thiazol-2-amine → 5-(Imidazo[2,1-b]benzothiazol-2-yl)-3-nitropyrocatechol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo(d)thiazol-2-amine | HCID 8706 | — |
| Reactant | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(Imidazo[2,1-b]benzothiazol-2-yl)-3-nitropyrocatechol | HCID 21459069 | — |
Reaction Steps
A mixture of 1.95 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone, 1.06 g of 2-aminobenzothiazole and 50 ml of ethanol is heated to boiling under reflux for 17 hours. The reaction mixture is then cooled to room temperature, whereupon the crystals are removed by filtration under suction. There is obtained 5-(imidazo[2,1-b]benzothiazol-2-yl)-3-nitropyrocatechol of m.p. 303°-305° (from N,N-dimethylformamide/methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05633371 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-aa4eda828af2427496961a45f8834596 |
| Source note | uspto-grants-1997_05 |