HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiophenol → 5-(2H-1,4-benzothiazin-3-yl)-3-nitropyrocatechol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiophenol | HCID 8713 | — |
| Reactant | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(2H-1,4-benzothiazin-3-yl)-3-nitropyrocatechol | HCID 135665321 | — |
Reaction Steps
A mixture of 2.78 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone, 1.51 g of 2-aminothiophenol and 50 ml of ethanol is heated to boiling under reflux for 1 hour. The reaction mixture is then cooled to room temperature, whereupon the crystals are removed by filtration under suction. There is obtained 5-(2H-1,4-benzothiazin-3-yl)-3-nitropyrocatechol of m.p. 302°-304° (from N,N-dimethylformamide/methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05633371 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-0f27e377bd8d438882b4fdae17e1503a |
| Source note | uspto-grants-1997_05 |