HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Acetate → 2-(3,4-dimethoxy-5-nitrophenyl)-4H-1-benzopyran-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | o-Acetylphenyl 3,4-dimethoxy-5-nitrobenzoate | HCID 21458954 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(3,4-dimethoxy-5-nitrophenyl)-4H-1-benzopyran-4-one | HCID 21459108 | — |
Reaction Steps
A solution of 2.0 g of o-acetylphenyl 3,4-dimethoxy-5-nitrobenzoate in 12.5 ml of glacial acetic acid is treated with 0.94 g of sodium acetate and held at the reflux temperature for 4 hours. After cooling the mixture is poured into ice-water. The separated crystals are filtered under suction. After recrystallization from ethyl acetate/hexane there is obtained 2-(3,4-dimethoxy-5-nitrophenyl)-4H-1-benzopyran-4-one in the form of colorless crystals of m.p. 216°-217°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05633371 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-705ed834130c4adcb591f79eeb956aff |
| Source note | uspto-grants-1997_05 |