HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86232726, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 15-Crown-5 | HCID 36336 | — |
| Reactant | Pyridine-2-sulfonyl Chloride | HCID 3787675 | — |
| Reactant | 4-Methyl-5-phenyl-1H-pyrrole-3-carbaldehyde | HCID 71362812 | — |
| Product | HCID 86232726 | HCID 86232726 | — |
Reaction Steps
By a reaction under similar conditions as in Reference Example 65 and using 4-methyl-5-phenyl-1H-pyrrole-3-carbaldehyde (185 mg), sodium hydride (60% in oil, 60 mg), 15-crown-5 (0.30 mL) and 2-pyridinesulfonyl chloride (231 mg) instead of 3-pyridinesulfonyl chloride hydrochloride, the title compound was obtained as an amorphous form (yield 262 g, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07498337B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-886f6cc7c36942c7934f749e5e49fb9b |
| Source note | uspto-grants-2009_03 |