Pyridine-2-sulfonyl Chloride → HCID 86630980, compound

HRID 1782304Notes

Reaction equation

HRID 1782304 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[NH:12][CH:11]=[C:10]([CH:13]=[O:14])[CH:9]=1.[N:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[S:21](Cl)(=[O:23])=[O:22]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:12]([S:21]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][N:15]=2)(=[O:23])=[O:22])[CH:11]=[C:10]([CH:13]=[O:14])[CH:9]=1

Participants

3

Reactant 2

HCID 3787675Pyridine-2-sulfonyl ChlorideHCID 469085935-(2-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde

Product 1

HCID 86630980HCID 86630980, compound

Procedure

By a similar reaction as in Reference Example 65 and using 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde (190 mg) and pyridine-2-sulfonyl chloride (231 mg), the title compound was obtained as a pale-red solid (yield 183 mg, 55%).

Workup

  1. customBy a similar reaction as in Reference Example 65

Sources & evidence

ORD record
ord-eee68b78c04747ad87d7082d10851e72
Source dataset
uspto-grants-2009_03
Patent number
US07498337B2

Reaction notes

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