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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1782328Generated: October 30, 2026

Sodium Carbonate → HCID 66974708, compound

https://huagongshe.com/reaction/1782328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CarbonateHCID 10340—
Reactant4-Cyanophenylboronic acidHCID 2734326—
Reactanttert-Butyl {[5-bromo-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamateHCID 57522258—
CatalystHCID 178418397HCID 178418397—
ProductHCID 66974708HCID 66974708—

Reaction Steps

By a similar operation as in Reference Example 79 and using tert-butyl {[5-bromo-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamate (430 mg), (4-cyanophenyl)boronic acid (176 mg), sodium carbonate (254 mg) and tetrakis(triphenylphosphine)palladium (57.8 mg), the title compound was obtained as a pale-yellow oil (yield 382 mg, 84%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07498337B2
Source datasetuspto-grants-2009_03
ORD IDord-c2be1ffdfb244784bfa2d5017652f812
Source noteuspto-grants-2009_03