HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Fluoro-2-nitrobenzene → HCID 69057747, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| Reactant | 2-Aminothiophene | HCID 97373 | — |
| Product | HCID 69057747 | HCID 69057747 | — |
Reaction Steps
Both paths start with a Gewald reaction to form appropriately substituted 2-amino-thiophenes (a). This type of reaction is described in Chem. Ber. 1965, 98, 3571-3577; Chem. Ber. 1966, 99, 94-100. The second step involves the reaction of 2-aminothiophene with 2-nitro-1-fluorobenzene (b), to give a 2-(2-nitro-anilino)thiophene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07498433B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-04e9fdd4be344ec89e6c72bfdcb0480a |
| Source note | uspto-grants-2009_03 |