HRID1782486

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID73833

Benzene, ((2-bromoethoxy)methyl)-

C9H11BrO

反应SMILES：OC(c1ccc2ccccc2c1)(c1ccc2ccccc2c1)C12CCN(CC1)CC2

HCID68961977

未命名化合物

PRODUCTS

产物

反应SMILES：OC(c1ccc2ccccc2c1)(c1ccc2ccccc2c1)C12CC[N+](CCOCc3ccccc3)(CC1)CC2.[Br-]

HCID11505381

未命名化合物

收率 25%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

Following the general procedure outlined in Example 3, 1-azabicyclo[2.2.2]oct-4-yl(di-2-naphthalenyl)methanol (0.063.7 g, 0.162 mmol) and 2-bromoethyl phenylmethyl ether (0.0384 mL, 0.243 mmol) in 2 CH3CN/3 CHCl3 (4.0 mL) were reacted to give the desired product (0.0246 g, 25.0%). EI-MS m/z 528(M+) Rt (2.36 min).

WORKUP

后处理

customwere reacted

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-6f103f309c7840c2a61752374acb7265
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07498440B2
来源说明: uspto-grants-2009_03

反应SMILES

[N:1]12[CH2:8][CH2:7][C:4]([C:9]([C:21]3[CH:30]=[CH:29][C:28]4[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=4)[CH:22]=3)([C:11]3[CH:20]=[CH:19][C:18]4[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=4)[CH:12]=3)[OH:10])([CH2:5][CH2:6]1)[CH2:3][CH2:2]2.[C:31]1([CH2:37][O:38][CH2:39][CH2:40][Br:41])[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>CC#N>[Br-:41].[OH:10][C:9]([C:21]1[CH:30]=[CH:29][C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=1)([C:11]1[CH:20]=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=1)[C:4]12[CH2:3][CH2:2][N+:1]([CH2:40][CH2:39][O:38][CH2:37][C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)([CH2:6][CH2:5]1)[CH2:8][CH2:7]2