HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluorobenzoic acid → 2,6-difluoro-N-[4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluorobenzoic acid | HCID 9796 | — |
| Reactant | 4-Methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylamine | HCID 11557499 | — |
| Product | 2,6-difluoro-N-[4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-benzamide | HCID 18440841 | 72% |
Reaction Steps
Pet-161 was prepared according to the general procedure described hereinabove and the procedure described above for the preparation of Pet-154, using 2,6-difluoro-benzoic acid and 4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylamine (Pet-10) as the starting materials, in an overall yield of 72%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07498445B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-08fd21063e4742b0825fdf63b8fd7d76 |
| Source note | uspto-grants-2009_03 |