2-Aminophenol → 2-(Isopropylamino)phenol

HRID 1782550Notes

Reaction equation

HRID 1782550 reaction equation
I[CH:2]([CH3:4])[CH3:3].[NH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[OH:12]>>[CH:2]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[OH:12])([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 58012-AminophenolHCID 6362Isopropyl iodide2×

Product 1

HCID 5860122-(Isopropylamino)phenol

Procedure

The same procedure as in Example 1 was repeated except that the molar ratio of 2-iodopropane to o-aminophenol was changed to 1.0, the 2-iodopropane was dropped over 3 h, and then the reaction mixture was stirred at room temperature for 2 h.

Sources & evidence

ORD record
ord-5fdff8ad94b1459fb6ebc4bbffce679d
Source dataset
uspto-grants-2009_03
Patent number
US07498467B2

Reaction notes

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